Table 1 Schema of the phiBIOTICS database entries

Name

Conventional name of enzybiotic

Recommended name

Full name recommended by UniProt database (submitted or approved)

Systematic name*

Enzyme systematic name according to IUBMB Enzyme Nomenclature

Alternative name

Other name(s) in use

UniProt ID

Identifier of corresponding entry in UniProt database

General mode of action

The overall mechanism of antimicrobial action

phiBIOTICS family

Proposed enzybiotic family based upon enzymatic activity

Reaction catalysed

Biochemical reaction catalysed by the enzybiotic

Source organism

Name of the organism from which the enzybiotic was obtained

Target organism

Name of the organism(s) against which the enzybiotic is effective

Disease

List of diseases caused by target organisms

State

Current state of research and application(s)

Reference

Paper(s) describing enzybiotics properties

Relevant studies

Antimicrobial agent

Name of applied enzybiotic(s) and other agents eventually

Study type

in vitro or in vivo

Model

Organism(s) used as experimental model

Administration*

Applied route of administration of the enzybiotics

Relevant results

Significant outcomes of the research study

Adverse effects and other issues*

Manifested side effects (e.g. toxicity, immunogenicity, health issues)

Reference

Paper(s) related to the study