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Figure 3 | BMC Microbiology

Figure 3

From: Integrin α5β1-fimbriae binding and actin rearrangement are essential for Porphyromonas gingivalis invasion of osteoblasts and subsequent activation of the JNK pathway

Figure 3

JNK pathway is activated in osteoblasts upon repeated P. gingivalis infection. A. P. gingivalis infected osteoblasts demonstrated stronger expression of phosphorylated JNK than uninfected control cells from day 7 to 21. Actin is the loading control. B. Quantitative densitometric analysis showing that the p-JNK/JNK ratio was significantly higher in infected osteoblasts compared with control cells. Abbreviations: PG, P. gingivalis; Ctrl, control, non-infected osteoblasts; D, day; JNK, c-Jun N-terminal kinase; p-, phosphorylated. * denotes P < 0.05.

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