Figure 3From: Integrin α5β1-fimbriae binding and actin rearrangement are essential for Porphyromonas gingivalis invasion of osteoblasts and subsequent activation of the JNK pathwayJNK pathway is activated in osteoblasts upon repeated P. gingivalis infection. A. P. gingivalis infected osteoblasts demonstrated stronger expression of phosphorylated JNK than uninfected control cells from day 7 to 21. Actin is the loading control. B. Quantitative densitometric analysis showing that the p-JNK/JNK ratio was significantly higher in infected osteoblasts compared with control cells. Abbreviations: PG, P. gingivalis; Ctrl, control, non-infected osteoblasts; D, day; JNK, c-Jun N-terminal kinase; p-, phosphorylated. * denotes P < 0.05.Back to article page