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Table 4 Virulence of selected mutant strains

From: Non-essential genes form the hubs of genome scale protein function and environmental gene expression networks in Salmonella entericaserovar Typhimurium

Strains

Description

1CI ± SD

JTR.452

yajD

1.2 ± 0.3

JTR.481

wraB & ychN

1.9 ± 0.7*

JTR.482

wraB & osmC

0.7 ± 0.2*

JTR.490

ychN & dcoC

1.4 ± 0.9

JTR.498

cbpA & osmC

1.4 ± 0.3

JTR.499

cbpA & dcoC

0.4 ± 0.1*

  1. 1The competitive index (CI) and its standard deviation (SD) were calculated by dividing the proportion of mutant colonies in the spleen by the proportion of mutant colonies in the inoculum used to infect the mice, as previously reported [75].
  2. *The CI is significantly different from 1, by one-sample t-test, indicating a significant change in the ability of the mutant strain to reside or propagate in mice with respect to the wild type.