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Figure 6 | BMC Microbiology

Figure 6

From: Deletion of the HAMP domains from the histidine kinase CaNik1p of Candida albicans or treatment with fungicides activates the MAP kinase Hog1p in S. cerevisiae transformants

Figure 6

Model of the activation of the HOG pathway via CaNIK1 or CaNIK1ΔHAMP, which were heterologously expressed in S. cerevisiae. In scheme A, the initial situation is shown resulting from expression of CaNik1p in S. cerevisiae. In scheme B, results from fungicide treatment of transformants expressing CaNik1p with point mutations in the conserved domains of histidine kinases were taken into consideration. In scheme C, the growth inhibition and the constitutive Hog1 phosphorylation in transformants, in which CaNIK1ΔHAMP was expressed, were considered.

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BMC Microbiology

ISSN: 1471-2180

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