Figure 1From: Deletion of the HAMP domains from the histidine kinase CaNik1p of Candida albicans or treatment with fungicides activates the MAP kinase Hog1p in S. cerevisiae transformantsSchematic representation of the role of different domains of CaNik1p for the protein activity. ATP binds to the HATPase_c domain, and a phosphate group is first transferred to the conserved phosphate accepting residue His510 of the HisKA domain and then to Asp924 of the REC domain.Back to article page