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Table 2 Modulated protein kinases in day 2 and day 8 spherules

From: Gene expression in human fungal pathogen Coccidioides immitis changes as arthroconidia differentiate into spherules and mature

Gene ID

FCa

FCb

C. immitis annotation

Classification gene

S. cerevisiae

CIMG_05093

−7.84

2.78

Serine/threonine-protein kinase; meiosis induction protein kinase

CMGC/RCK/MAK

IME2 *

CIMG_09053

−6.68

6.18

Kinase domain containing protein

CAMK/NNK1

NNK1

CIMG_07296

−5.60

5.26

Protein kinase domain containing protein

CAMK/CAMKL/MARK

YPL150W

CIMG_01236

−5.46

--

PAK kinase

STE/STE20/PAKA

STE20 *

CIMG_00940

−5.28

--

Protein kinase

Other/WEE/SWE1

SWE1 **

CIMG_07521

−4.67

2.94

Protein kinase domain containing protein; serine/threonine protein kinase 24

STE/STE20/YSK

SPS1 *

CIMG_04027

−4.65

3.81

serine/threonine protein kinase ssp1

Other/CAMKK

None

CIMG_03267

−4.55

--

serine/threonine protein kinase

CAMK/CAMKL/Kin4

KIN4 **

CIMG_07588

−4.52

--

Kinase domain containing protein; checkpoint kinase

Other/TTK

MPS1 **

CIMG_01204

−4.34

4.02

protein kinase

AGC/YANK

None

CIMG_08909

−4.14

3.06

Protein kinase, sky 1

CMGC/SRPK

SKY1

CIMG_03947

−4.04

3.64

serine/threonine protein kinase

CAMK/CAMKL/PASK

PSK1

CIMG_03602

−3.98

3.70

Ran1-like protein kinase

Other/RAN/VHS1

VHS1 **

CIMG_04103

−3.97

--

cytokenesis protein sepH

STE/STE11/CDC15

CDC15 **

CIMG_08220

−3.96

6.13

serine/threonine protein kinase ATG1

Other/ULK/ULK

ATG1

CIMG_06932

−3.81

2.58

MAP kinase kinase kinase SskB

STE/STE11/MEKK4

SSK2

CIMG_13010

−3.74

3.93

serine/threonine protein kinase

Other/RAN/KSP1

KSP1 *

CIMG_09191

−3.52

2.50

Protein kinase

Other/HAL/HRK1

HRK1

CIMG_09469

−3.36

--

Kinase domain containing protein

Other/PEK

None

CIMG_03857

−3.08

--

Kinase domain containing protein

Other/NAK/BIKE

PAK1

CIMG_02369

−3.05

--

Response regulator receiver RIM15p

AGC/NDR/RIM15

RIM15 **

CIMG_05623

−2.74

--

Serine threonine protein kinase

CAMK/CAMKL/AMPK

SNF1

CIMG_00136

−2.71

--

Kinase domain containing protein

CMGC/DYRK/DYRK2

YAK1

CIMG_02925

−4.55

--

Protein kinase domain containing protein

CMGC

None

CIMG_05694

3.01

−3.83

Protein kinase domain containing protein

CMGC/SRPKL1

None

CIMG_05990

2.48

--

RWD domain protein

Other/PEK/GCN2

GCN2

  1. * Indicates a gene involved in the sexual cycle in Saccharomyces; ** Indicates a gene involved in mitosis in Saccharomyces; a) Indicates a comparison between day 2 spherules and mycelia; b) indicates a comparison between day 8 and day 2 spherules; --, indicates that the gene is not modulated.