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Figure 4 | BMC Microbiology

Figure 4

From: Dual effect of Lutzomyia longipalpis saliva on Leishmania braziliensis infection is mediated by distinct saliva-induced cellular recruitment into BALB/c mice ear

Figure 4

Cytokine production by the draining lymph nodes after different inoculums of SGE. BALB/c mice inoculated i.d. once (SGE-1X ) or three times (SGE-3X) with Lutzomyia longipalpis SGE or with PBS (control) were challenged with 105L. braziliensis stationary phase promastigote forms. At the end of the 7th week post-infection, draining lymph node cells were harvested and restimulated in vitro with L. braziliensis antigen (5 μg/ml) or medium for 72 h. IL-10 (A) and IFN-γ (B) levels in the supernatant were determined by ELISA assay. The results are expressed as the mean ± SEM of at least two independent experiments using four to five mice per group (n = 4-5 mice per group). #P < 0.05 compared with medium-only stimulus. *P < 0.05 compared with the SGE-1X group.

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BMC Microbiology

ISSN: 1471-2180

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