Figure 2

Schematic representation of study design and mode of sampling. A pooled stool sample was assigned to the three study arms (Clindamycin for 7 days followed by VSL#3 for 7 days, Clindamycin + VSL#3 for 7 days, no therapy control for 7 days). Dialysis fluid and lumen samples for metabolic analysis (SCFA, BCFA, lactate, ammonia) were collected daily, lumen samples for microbial analysis were sampled before therapy and at the end of each 7 days period.