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Table 2 Major seroreactive proteins of C. burnetii on microarray probed with Q fever patient sera

From: Potential serodiagnostic markers for Q fever identified in Coxiella burnetiiby immunoproteomic and protein microarray approaches

 

Fluorescence intensity

Sensitivitya

Protein

Normal

(n = 25)

Acute early

(n = 25)

Acute late

(n = 25)

Convalescent

(n = 6)

Acute early

Acute late

Convalescent

GroEL

114 ± 84

1548 ± 1996

3915 ± 3462

642 ± 382

84%

88%

83%

YbgF

104 ± 83

752 ± 1308

1517 ± 1946

1176 ± 1061

44%

72%

67%

RplL

85 ± 88

277 ± 396

949 ± 1174

185 ± 119

20%

68%

17%

Mip

137 ± 78

324 ± 233

611 ± 669

237 ± 157

44%

60%

17%

Com1

70 ± 84

120 ± 326

461 ± 525

253 ± 176

12%

52%

50%

OmpH

141 ± 95

210 ± 195

676 ± 1192

398 ± 540

20%

48%

17%

DnaK

95 ± 91

143 ± 122

371 ± 480

165 ± 105

16%

48%

17%

  1. aSensitivity was calculated as the percentage (the number of microarray-positive sera divided by the number of sera of patients with Q fever)