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Figure 1 | BMC Microbiology

Figure 1

From: Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli

Figure 1

The oxidative stress sensitive skn-1(zu169) mutant, with defects in response to dietary restriction, shows a life span extension in response to the GD1 diet. Wild-type N2 (squares) and skn-1(zu169) −/− mutant worms (triangles) were fed either OP50 (black) (N2, n = 164; skn-1(zu169) −/−, n = 153) or GD1 (grey) (N2, n = 135; skn-1(zu169) −/−, n = 131) from the L4 stage. N2 worms fed GD1 showed a 67% increase in mean life span as compared to N2 worms fed OP50 (a, p < .0001). skn-1(zu169) −/− mutants fed GD1 showed a 50% increase in mean life span compared to N2 worms fed OP50 (a, p < .0001). skn-1(zu169) −/− fed OP50 showed an 11% decrease in mean life span as compared to N2 fed OP50 (a, p < .0001). skn-1(zu169) −/− fed GD1 showed a 69% increase in mean life span compared to mutants fed OP50 (b, p < .0001). Data were subjected to one-way ANOVA with Fisher’s test at a significance level of p < 0.05.

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BMC Microbiology

ISSN: 1471-2180

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