Figure 3
Survival of immunosuppressed mice with disseminated candidiasis treated with antifungal drugs. Animals were treated with 100 mg/kg of cyclophosphamide and infected with 103 yeasts of C. albicans (INF). The animals were treated with 5 mg/kg of gomesin (GOM), 20 mg/kg of fluconazole (FLUCO) or the combination of 5 mg/kg gomesin and 20 mg/kg of fluconazole. As controls, infected animals (NINF) received PBS and uninfected animals received PBS and gomesin 5 mg/kg. * Indicates statistical significance (Long-rank test, P < 0.05).