Skip to main content
Figure 1 | BMC Microbiology

Figure 1

From: Enhancement of carotenoid production by disrupting the C22-sterol desaturase gene (CYP61) in Xanthophyllomyces dendrorhous

Figure 1

Mevalonate pathway, astaxanthin and ergosterol biosynthesis. The arrows represent the catalytic step with the respective enzyme-encoding gene described in X. dendrorhous (gene names without brakets and written in black) and S. cerevisiae (genes between brackets and written in blue). The represented X. dendrorhous genes with their Genbank accession number in square brackets are: HMGR [AJ884949], IDI [DQ235686], crtE [DQ012943], crtYB [DQ016503], crtI [Y15007], crtS [EU713462] and crtR [EU884133]. The X. dendrorhous HMGS, FPS and SQS gene sequences are submitted in patents [DI059433.1, DI032788.1 and EA489199, respectively]. The following S. cerevisiae genes are represented: ERG10 [NM_001183842], ERG13 [NM_001182489], ERG12 [AN: NM_001182715], ERG8 [NM_001182727], MVD1 [NM_001183220], ERG20 [NM_001181600], ERG1 [M64994], ERG7 [U23488.1], ERG11 [NM_001179137], ERG24 [NM_001183118], ERG25 [NM_001181189], ERG26 [NM_001180866], ERG27 [NM_001181987], ERG6 [NM_001182363], ERG2 [NM_001182709], ERG3 [NM_001181943], ERG5 [NM_001182511], and ERG4 [NM_001180877]. Abbreviations: 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA), mevalonate (MVA), mevalonate-5-phosphate (MVA-P), mevalonate-5-pyrophosphate (MVA-PP), isopentenyl-pyrophosphate (IPP), dimethylallyl-pyrophosphate (DMAPP), geranyl-pyrophosphate (GPP), farnesyl-pyrophosphate (FPP), geranylgeranyl-pyrophosphate (GGPP).

Back to article page