Figure 2

Binding of B. burgdorferi strains B31 and N40D10/E9 to C6 glioma and T/C-28a2 chondrocyte cell monolayers was significantly reduced on pretreating these cells with chondroitinase ABC but remain unaffected on their pretreatment with heparinase I. The experiments were repeated at least three times using four replicates for each treatment. Each value represents the mean ± SD of quadruplicate samples. Asterisks indicate significant reduction (p < 0.05) in binding percentage relative to mock-treated cells as determined by t-test for pairwise comparison of samples with unequal variance.