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Table 2 Shannon diversity index and measurement of Evenness of the fecal microflora prior to and after challenge with C. rodentium (CR, in wild type (WT) and MMP-9 gene knockout mice

From: Matrix metalloproteinase 9 contributes to gut microbe homeostasis in a model of infectious colitis

Experimental group

Shannon-seiner diversity

Evenness

Sham WT

1.88 ± 0.10

0.81 ± 0.02

CR WT 10d

1.32 ± 0.14*

0.65 ± 0.06*

CR WT 30d

1.67 ± 0.08

0.80 ± 0.02

Sham MMP-9−/−

1.59 ± 0.05

0.81 ± 0.01

CR MMP-9−/− 10d

1.83 ± 0.10

0.87 ± 0.03 Ψ

CR MMP-9−/− 30d

1.70 ± 0.09

0.91 ± 0.01 Ψ

  1. N = 3-8 in each experimental group
  2. * p < 0.05 vs WT uninfected and WT 30 days PI
  3. Ψ p < 0.05 vs MMP-9−/− uninfected