Table 1 Genes carried on plasmids involved in S. aureus survival and adaptation
Gene Class | Gene | Accession Number/ Locus Tag | Function |
|---|---|---|---|
Antimicrobial resistance, biocide resistance and heavy metal resistance | aacA/aphD | VRA0030 | Gentamicin & Kanamycin Resistance |
aadD | PGO1_p21 | Neomycin & Kanamycin Resistance | |
aadE | SAP049A_002 | Aminoglycoside Resistance | |
aphA | SAP049A_001 | Neomycin & Kanamycin Resistance | |
arsC | SAP013A_020 | Arsenic Resistance | |
bcrA | SAP049A_007 | Resistance to Bacitracins | |
blaZ | pBORa53p07 | Penicillin Resistance | |
ble | PGO1_p20 | Bleomycin Resistance | |
cadA | SATW20_p1220 | Cadmium Resistance | |
cadDX | pKH18_01 _02 | Cadmium Resistance | |
cat | pTZ4_p2 | Chloramphenicol Resistance | |
cfr | EF450709 | Chloramphenicol, Lincosamides & Linezolid Resistance | |
dfrA | PGO1_p48 | Trimethoprim Resistance | |
dfrK | FN377602 | Trimethoprim Resistance | |
ermB | SAP013A_023 | MLS Group Resistance | |
ermC | pKH19_p2 | MLS Group Resistance | |
fosB | pTZ2162_25 | Fosomycin Resistance | |
fusB | pUB101_p23 | Fusidic Acid Resistance | |
IP1 | pBORa53p09 | Immunity Protein | |
IP2 | SAP099A_005 | Immunity Protein | |
linA | pKH21_p2 | Linezolid Resistance | |
mco | SAP019A_028 | Copper Resistance | |
merA | SAP026A_033 | Mercury Resistance | |
mphBM | SAP052A_035 | Macrolide Resistance | |
mupA | SAP082A_042 | Mupirocin Resistance | |
qacA | SAP066A_020 | Biocide Resistance | |
qacC | VRA0026 | Biocide Resistance | |
qacJ | pNVH01_p2 | Biocide Resistance | |
sat | SAP049A_002 | Streptothricin Resistance | |
str | pS194_p1 | Streptomycin Resistance | |
tcaA | SAP082A_032 | Teichoplanin Resistance | |
tetK | pKH17_02 | Tetracycline Resistance | |
tetL | FN377602 | Tetracycline Resistance | |
tetM | SAPIG0957 | Tetracycline & Minocycline Resistance | |
vanB | VRA0040 | Vancomycin Resistance | |
vatA | M36022 | Streptogramin Resistance | |
vgaA | pVGA_p2 | Streptogramin Resistance | |
vgaB | U82085 | Streptogramin Resistance | |
Transfer | traA | SAP082A_013 | Plasmid conjugation |
traB | SAP082A_012 | Plasmid conjugation | |
traC | SAP082A_011 | Plasmid conjugation | |
traD | SAP082A_010 | Plasmid conjugation | |
traE | SAP082A_009 | Plasmid conjugation | |
traF | SAP082A_008 | Plasmid conjugation | |
traG | SAP082A_007 | Plasmid conjugation | |
traH | SAP082A_006 | Plasmid conjugation | |
traI | SAP082A_005 | Plasmid conjugation | |
traJ | SAP082A_004 | Plasmid conjugation | |
traK | SAP082A_003 | Plasmid conjugation | |
traL | SAP082A_002 | Plasmid conjugation | |
traM | SAP082A_001 | Plasmid conjugation | |
type III R-M | SAP039A_002 | Prevents Survival of Foreign DNA in Host Bacterium | |
mob-I | AF447813 | Mobilisation L gene | |
cas3 | SAP039A_001 | Helicase of the CRISPR region | |
abiK | SAP058A_004 | Prevents Bacteriophage Replication | |
C55 | pETB_p42 | Lantibiotic System that Kills other Bacteria | |
Toxins | ETB | pETB_p01 | Toxin |
entA | SAP048A_010 | Toxin | |
entG | SAP048A_007 | Toxin | |
entJ | SAP048A_008 | Toxin | |
entP | SAP099A_058 | Toxin | |
Adherence | sdrE | SAP041A_028 | Adherence to Host Cells |
Anti-adhesin | SAP057A_026 | Prevents Adherence |