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Table 4 Accuracy of final DGGE model* in predicting API status at age 3 years

From: Denaturing gradient gel electrophoresis of neonatal intestinal microbiota in relation to the development of asthma

 

API index

 

N

 
 

Pos

Neg

  

DGGE model Pos.

13

19

32

PPV = 41%

DGGE model Neg.

11

67

78

NPV = 86%

Total

24

86

110

 
 

54% S

78% Sp

 

X2, p = 0.002

  1. Overall correct classification: 80/110 = 73%
  2. API prevalence: 24/110 = 22%
  3. Final DGGE model:
  4. Positive: presence of band 60.1 (Clostridium coccoides subcluster XIVa) or band 45.9 (Bacteroides fragilis subgroup)
  5. Negative: absence of band 60.1 (Clostridium coccoides subcluster XIVa) and band 45.9 (Bacteroides fragilis subgroup)
  6. N: number of cases
  7. PPV: positive predictive value
  8. NPV: negative predictive value
  9. S: sensitivity
  10. Sp: specificity