|  | Experimental period |
---|
 |  | Stab | Sal | Ecol I | Ecol II | Bif | Inulin |
---|
R1
| Â | Â | Â | Â | Â | Â |
TER | 1-3 h | 247 ± 24a | 144 ± 24bc | 143 ± 22bc | 114 ± 14c | 167 ± 34b | 121 ± 13bc |
 | 24 h | 127 ± 23a | 69 ± 20b | 55 ± 11b | 36 ± 4b | 130 ± 47a | 65 ± 14b |
SCFAs* (A:P: B ) |  | 138 ± 6a
(54:11:
34
)
| 179 ± 6a
(44:7:
50
)
|
R2
| Â | Â | Â | Â | Â | Â |
TER | 1-3 h | 266 ± 19a | 135 ± 29b | 144 ± 17b | 96 ± 4c | 158 ± 8b | 142 ± 29b |
 | 24 h | 205 ± 34a | 74 ± 17c | 52 ± 4cd | 34 ± 8d | 115 ± 19b | 87 ± 11bc |
SCFAs* (A:P: B ) |  | 172 ± 6b
(54:14:
32
)
| 245 ± 6b
(45:12:
43
)
|
R3
| Â | Â | Â | Â | Â | Â |
TER | 1-3 h | 240 ± 24a | 124 ± 30bc | 141 ± 16b | 91 ± 6c | 145 ± 8b | 121 ± 30bc |
 | 24 h | 190 ± 37a | 75 ± 17cd | 77 ± 13c | 32 ± 11d | 119 ± 30b | 91 ± 25bc |
SCFAs* (A:P: B ) |  | 180 ± 13b
(55:14:
31
)
| 234 ± 11b
(46:11:
4
3)
|
- Mean transepithelial electrical resistance (TER; expressed in Ω cm2) ± SD were measured after incubation of HT29-MTX cell monolayers for 1-3 h (N = 18) and 24 h (N = 6) with effluents retained from (R1) proximal, (R2) transverse and (R3) distal colon reactors of F1 and F2 during the last three days of each experimental period. Values with different letters in a row of the same reactor are significantly different according to the Tukey-Kramer-HSD test (P < 0.05). *No treatment effects (except for inulin addition) were detected on total short chain fatty acid (SCFA) concentrations (expressed in mM). Mean SCFA concentrations ± SD and (A) acetate: (P) propionate: ( B ) butyrate ratios measured during the last three days of non-inulin (N = 33) and inulin (N = 3) periods are therefore presented. Values with different letters in the same column of different reactors are significantly different with the Tukey-Kramer-HSD test (P < 0.05). (Stab) initial system stabilization periods, (Sal) Salmonella infection periods, (Ecol) E. coli L1000 treatments, (Bif) B. thermophilum RBL67 treatments, (Inulin) prebiotic inulin treatment.