Intestinal dysbiosis and reduced immunoglobulin-coated bacteria associated with coeliac disease in children

BMC Microbiology

Table 1 Faecal microbiota composition of untreated and treated CD patients and age-matched healthy controls assessed by FISH and FCM

Microbial groups	Specific group-probed cells/EUB-388 cells (%)¹
	Untreated CD (n = 24)		Treated CD (n = 18)		Control (n = 20)
	Median	Range	Median	Range	Median	Range
Bifidobacterium	7.73	22.08-3.27	9.20	33.82-1.58	12.54	33.68-6.94
C. histolyticum	5.26	27.61-0.71	9.41	39.60-2.95	11.61	35.69-0.16
C. lituseburense	3.23	27.24-0.17	4.41	29.85-0.28	6.83	19.56-1.05
Lactobacillus-Enterococcus	1.94	10.93-0.14	1.12	9.30-0.22	1.76	16.47-0.25
Staphylococcus	10.36	37.38-0.89	16.49	42.91-0.51	18.04	41.32-0.19
Bacteroides-Prevotella	3.54	20.85-0.80	2.61	15.07-0.25	2.32	5.53-0.33
E. coli	5.20	23.42-0.48	6.39	28.77-0.55	7.32	28.26-1.10
F. prausnitzii	6.03	37.50-1.07	11.09	37.84-2.95	13.88	37.08-2.32
Sulphate-reducing bacteria	9.58	38.02-2.84	9.82	41.74-2.09	10.02	36.92-2.92

¹ Data were expressed as proportions of bacterial cells hybridising with group-specific probes to total bacteria hybridising with EUB probe 338.
* Statistical significant differences were calculated using the Mann-Whitney U-test and established at P < 0.050.

ISSN: 1471-2180