Table 2 Features of human AMPs used in this study
From: Differential activity of innate defense antimicrobial peptides against Nocardia species
AMP | class/structure | origin | expression pattern |
|---|---|---|---|
LL-37 | cathelicidin, α-helical peptide | human | neutrophils, monocytes/macrophages (constitutive); epithelial cells of respiratory, gastrointestinal and urogenital tract, keratinocytes (inducible) |
HNP 1-3 | α-defensins, β-sheet peptides | human | neutrophils (constitutive) |
hBD-3 | β-defensin, β-sheet peptide | human | epithelial cells of respiratory and gastrointestinal tract, keratinocytes (inducible) |
indolicidin | linear, tryptophan- and proline-rich peptide | bovine | neutrophils (constitutive) |
LAP | β-defensin, β-sheet peptide | bovine | epithelial cells of respiratory and gastrointestinal tract, mammary gland (inducible) |
TAP | β-defensin, β-sheet peptide | bovine | epithelial cells of respiratory tract (inducible) |