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Table 1 The distribution and similaritya of mycobacterial rhomboids

From: Rhomboid homologs in mycobacteria: insights from phylogeny and genomic analysis

 

Orthologs of Rv0110(rhomboid protease 1)

   

Query: Rv0110

Query: Rv1337

Species/strain

Rhomboid

Length

%Identity

E-value

%Identity

E-value

bH37Rv

Rv0110

284

100

5e-143

26

3e-06

cBCG Tokyo

JTY_0114

284

100

3e-143

26

3e-06

M. bovis

Mb0114

284

100

3e-143

26

3e-06

M.ulcerans †

MUL_4822

254

78

5e-104

27

1e-04

M. marinum

MMAR_0300

289

77

1e-103

26

2e-06

dM.sp. JLS

Mjls_5529

289

67

7e-97

NS

5e-06

eM.sp. Kms

Mkms_5237

289

66

2e-96

NS

3e-06

M. smegmatis

MSMEG_5036

250

64

8e-90

NS

7e-09

M. vanbaalenii

Mvan_5753

290

61

6e-77

NS

6e-08

M. gilvum

Mflv_1071

279

61

7e-73

NS

2e-06

M. abscessus

MAB_0026

287

38

7e-38

NS

1e-04

 

Orthologs of Rv1337 (rhomboid protease 2)

H37Rv

Rv1337

240

27

7e-06

100

7e-137

BCG Tokyo

JTY_1373

240

27

7e-06

100

7e-137

M. bovis

Mb1372

240

27

7e-06

100

7e-137

M. marinum

MMAR_4059

222

26

8e-07

83

2e-106

M. avium †

MAV_1554

223

28

9e-05

75

7e-95

M. leprae †

ML1171

238

27

1e-04

73

7e-94

fMAP†

MAP2425c

223

NS

1e-04

74

6e-91

M. smegmatis

MSMEG_4904

219

NS

1e-05

73

9e-89

M.sp. JLS

Mjls_3833

229

26

1e-04

67

7e-81

M.sp. Kms

Mkms_3921

229

26

1e-04

67

7e-81

M. vanbaalenii

Mvan_4290

225

NS

4e-05

67

9e-77

M. gilvum

Mflv_2355

225

27

7e-04

66

9e-68

M. abscessus

MAB_1481

225

NS

8e-05

61

4e-67

  1. a: In comparison to Rv0110 and Rv1337 of M. tuberculosis H37Rv; lengths refer to number of amino acids
  2. b: Mycobacterium tuberculosis
  3. c: Mycobacterium bovis
  4. d: Mycobacterium species Jls
  5. e: Mycobacterium species Kms
  6. f: Mycobacterium avium subspecies Paratuberculosis
  7. †: Species with one rhomboid
  8. NS: Not Significant (< 10% identity).