Frequent associations between CTL and T-Helper epitopes in HIV-1 genomes and implications for multi-epitope vaccine designs

Table 4 Distribution of unique association rules according to genes involved in each association rule.

	Gag only	Pol only	Nef only	Gag-Pol	Gag-Env	Gag-Nef	Pol-Env	Pol-Nef	Gag-Pol-Nef	Total*
Association rules with 2 epitopes	46	24	1	55	3	5	1	3	0	138
Association rules with 3 epitopes	104	160	0	768	1	33	0	23	56	1145
Association rules with 4 epitopes	108	135	0	1699	0	29	0	23	104	2098
Association rules with 5 epitopes	73	47	0	1551	0	11	0	4	33	1719
Association rules with 6 epitopes	29	6	0	753	0	2	0	0	3	793
Association rules with 7 epitopes	5	0	0	211	0	0	0	0	0	216
Association rules with 8 epitopes	0	0	0	31	0	0	0	0	0	31
Association rules with 9 epitopes	0	0	0	2	0	0	0	0	0	2
Total	365	372	1	5070	4	80	1	53	196	6142

* There were no epitope associations in the following categories: Env only, Nef-Env, Gag-Pol-Env, Gag-Nef-Env, Pol-Nef-Env, Gag-Pol-Env-Nef
^$ Detailed break-up of number of associations based on epitope type and genes involved is given in additional file 4

ISSN: 1471-2180