Figure 3From: Acanthamoeba produces disseminated infection in locusts and traverses the locust blood-brain barrier to invade the central nervous systemInvasion of the locust brain by Acanthamoeba is associated with disruption of the outer capsule of the brain. (A) Intact blood-brain barrier in control locusts (pointed by arrows). (C) Damaged blood-brain barrier of infected brain (pointed by arrows) with two amoebae inside the brain (indicated by arrowheads). (B) &(D) amoebae (indicated by arrowheads) appearing to penetrate the brain via broken blood-brain barrier. Note that the above images are representative micrographs of the genotype T4, but, similar results were observed with the T1 genotype. Magnification is × 400.Back to article page