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Figure 4 | BMC Microbiology

Figure 4

From: Transcellular transport of West Nile virus-like particles across human endothelial cells depends on residues 156 and 159 of envelope protein

Figure 4

Effect of single amino acid substitutions in E protein on the transport of VLPs. HUVEC were exposed to mutant VLPs. After 24 h, media at the lower chamber were collected and subjected to IFU assay. (A) Transport of mutant 6-LP VLPs. *represents p < 0.01 (versus 6-LP). (B) Transport of mutant Eg VLPs. * and ** represent p < 0.01 and p < 0.05, respectively (versus Eg). The graphs show the mean of three determinations. The error bars show SD. The results are representative of 2 independent experiments.

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