Figure 5From: Immunization with a dominant-negative recombinant Herpes Simplex Virus (HSV) type 1 protects against HSV-2 genital disease in guinea pigsProtection from latent viral infection in guinea pigs immunized with CJ9-gD. Sixty days after challenge, 12 lower lumbar and sacral dorsal root ganglia (DRG) per guinea pig were harvested from all 8 immunized guinea pigs and the 2 surviving mock-immunized controls. The whole DNA was extracted and quantified for the presence of latent viral DNA using quantitative real-time PCR. The amount of viral DNA per guinea pig (A) was determined. The results are indicated as mean values ± SEM. P-value was assessed by Student's t-test (* p < 0.0001).Back to article page