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Table 1 Recovered Bacteria (CFU) from Mice infected in the skin with CS101 sagA/pel::Tn917*

From: Mouse skin passage of a Streptococcus pyogenes Tn917 mutant of sagA/pel restores virulence, beta-hemolysis and sagA/pel expression without altering the position or sequence of the transposon

Time (h)

Mouse

Spleen

Kidney

Liver

 

1

0

0

0

4

2

200

140

124

 

3

0

0

0

 

1

0

0

0

8

2

361

2

5

 

3

0

3

0

 

1

0

0

0

12

2

90

7

3

 

3

0

0

0

 

1

15

0

1

24

2

59

0

0

 

3

0

0

0

 

1

0

0

0

48

2

0

0

0

 

3

0

0

0

 

1

0

0

0

72

2

136

15

0

 

3

115

2

12

 

4

>>

72

76

  1. *The recovered isolates were erythromycin resistant ">>" = too numerous to count